CIP & SIP Installations

  Impeccable cleaning of all production elements (tanks, pipes, pumps, etc.) is of fundamental importance in the pharmaceutical industry. Only strict adherence to production hygiene guarantees quality of manufactured products.

  Therefore, the CIP / SIP installations must be properly designed for each specific production in order to optimize the process of controlled non-demountable cleaning.

  Operatingbasis

  The parameters of temperature, flow rate, pressure, concentration of chemical agents and dosing time are most scrupulously monitored by the system, granting the ability to configure many options, which allows not only to program the process of washing and sterilization, but makes the process cyclic, reliable, verifiable and validated.

  SIP sterilization of the production equipment is conducted with the use of pure steam which is generated by the steam generator. The sterilization cycle, as well as the washing process, is controlled by a programmable sequencer that manages each process phase.

  Design and specifications of a typical mobile installation
  Mobile CIP installation:

• Two tanks of 250 liters each, made out of AISI 316 steel, with a heating jacket, used for the preparation of solutions.
• Conical bottom.
• Electric heaters inside the tank.
• Peristaltic, piston or diaphragm pump for dosing the concentrates.
• Pressure pump.
• Disc valves made out of AISI 316 steel, with pneumatic butterfly valves and C-TOP control devices.
• Frame made out of AISI 316 steel, mounted on wheels.
• Installed filter on the return line.
• Automatic control of temperature and conductivity in the return lines.
• Level sensors in the tanks.
• Flow control installed on the return line.
• Pressure gauge on the pump outlet.
• 6-inch touchscreen.
• Monitoring system that uses PLCs manufactured by Siemens / Omron / Schneider Electric.
• The installation performs 5 programs: preparation, short-time washing of the tanks and of the production lines, long-time washing of the tanks and of the production lines. Manual activation of the valves. Visualization of the installation status. Modification of parameters.

  Options

• Recirculation inside the tank using a pump.
• An additional tank for dosing sterilizing agents.
• Data exchange between the CIP / SIP control panel and other control systems of the enterprise.
• Single-seated, double-seated or diaphragm valves instead of the butterfly valves.
• Tubular heat exchanger.
• Different configurations for the tanks.
• Control on the supply line.
• Registration of the operating data.
• Stationary stations.

  Used materials

• Parts that get in contact with the medium: AISI 316L stainless steel
• Other parts: AISI 304 stainless steel
• Insulation: mineral wool
• Seals (valves, pumps, connecting flanges): ethylene-propylene rubber, according to the FDA 177.2600 standard.